Product Tag - Aldactone (Spironolactone)


Aldactone (Spironolactone)

The drug “Aldactone” is a potassium-sparing diuretic. In medical practice it is used to get rid of arterial hypertension and other pathologies. Before using the medication it is important to carefully read the instructions for use and consult a doctor who will determine the permissibility of using the medication.

Aldactone composition and form

The drug is released in tablet form.

Produced “Aldakton” in the form of round tablets. Each tablet contains an active component of spironolactone in the amount of 25, 50 or 100 milligrams. Additional components are corn starch, magnesium stearate and lactose. The medication is packaged into cardboard boxes, each of which contains 2 blisters for 10 or 20 tablets.

Indications for use

According to the instructions for use, “Aldactone” is prescribed for the therapy of the following conditions:

  • nephrotic syndrome;
  • edema caused by heart disease;
  • puffiness due to cirrhosis of the liver;
  • swelling that is formed due to the period of pregnancy;
  • persistent increase in blood pressure;
  • preventive measures to develop an increased concentration of potassium in the blood.
  • What should necessarily pay attention to departures taking Aldactone (or other potassium-sparing diuretics), so this is the fact that in parallel you can not take the chemical potassium preparations, tk. this can lead to a life-threatening increase in the level of potassium in the body.
  • It should be noted that Aldactone possesses both antiandrogenic qualities, and as a result lowers the level of androgens in the blood. Bodybuilders use this property of Aidactone in order to minimize the phenomenon of musculation with steroid “courses”, as well as for the return of femininity after them. Men have another problem: the ratio of androgens-estrogens in favor of after-effects is changing, frequent cases of Aldactone administration in men are painful swelling of the nipples up to gynecomastia.
  • Other possible side effects of Aldactone: negative blood pressure, muscle cramps, dizziness, gastrointestinal disorders, vomiting, irregular heartbeat, weakness. However, the side effects of potassium-sparing diuretics are significantly less than thiazides and “looping agents”.

Side effects

From the digestive system: nausea, vomiting, abdominal pain, gastritis, ulceration and bleeding in the digestive tract, intestinal colic, diarrhea or constipation.

From the side of the central nervous system: dizziness, drowsiness, lethargy, headache, inhibition, ataxia.

On the part of metabolism: increased urea concentration, hypercreatininaemia, hyperuricemia, water-salt metabolism and KChR (metabolic hypochloraemic acidosis or alkalosis).

On the part of the hematopoiesis system: megaloblasticosis, agranulocytosis, thrombocytopenia.

From the endocrine system: with prolonged use – gynecomastia, erectile dysfunction in men; in women – dysmenorrhea, amenorrhea, metrorrhagia in menopause, hirsutism, coarsening of the voice, tenderness of the mammary glands, breast carcinoma.

Allergic reactions: urticaria, maculopapular and erythematous rashes, drug fever, pruritus.

Other: muscle spasms, decreased potency.

Interaction with other drugs

The most common negative effect of taking Aldactone together with other drugs is hypokalemia. The development of the disease can trigger the intake of a diuretic and potassium-containing drugs (including vitamin complexes and substitutes. Uncontrolled administration of Aldactone with other drugs can cause a sharp and severe decrease in pressure of the stool), ACE inhibitors, lazartone, eprosartan and candesartan.

With the simultaneous administration of Aldactone with other antihypertensive drugs, their effect is mutually reinforced.

If the drug is taken simultaneously with anticoagulants and salicylates, the diuretic effect for the body is reduced.

Reception of the drug enhances the effect of tryptorelin, buserelin, gonadorelin.

The simultaneous administration of Aldactone and digitoxin is capable of both increasing and decreasing the efficacy of the latter, as well as provoking an increase in the concentration of digoxin in the blood.